TARE (Transarterial Radioembolization)

Selective intra-arterial radiation delivering high-dose tumor therapy while preserving healthy liver tissue

TARE: Targeted Radiation Therapy Delivered Through the Liver’s Blood Supply

Transarterial Radioembolization (TARE) is a minimally invasive treatment in which radioactive microspheres (Y-90) are delivered directly into the arteries supplying liver tumors. This technique allows concentrated internal radiation to be deposited within the tumor while sparing healthy liver tissue. By combining the principles of embolization and radiotherapy, TARE offers effective control for primary liver cancer and metastatic liver lesions that are not amenable to surgery or ablation.

Precision Treatment for Hepatocellular Carcinoma and Liver-Dominant Tumors

TARE is particularly effective for Hepatocellular Carcinoma (HCC), especially in patients with preserved liver function but inoperable disease. It provides sustained tumor necrosis, reduces tumor size, and may serve as a bridge to liver transplantation. In metastatic cancers—such as colorectal cancer, neuroendocrine tumors, and cholangiocarcinoma—TARE helps control liver-dominant disease and improves survival outcomes. Its targeted approach reduces systemic toxicity compared to chemotherapy.

Minimally Invasive, Personalized Therapy With Proven Clinical Outcomes

TARE is performed through a catheter-based approach, resulting in minimal discomfort and rapid recovery. Each treatment is customised after a detailed mapping angiogram to evaluate blood flow and prevent non-target radiation. Clinical studies demonstrate high response rates, improved quality of life, and long-term disease control in selected patients. The therapy is well tolerated, making it suitable even for patients who have exhausted other treatment options.

How TARE Works: Precision Radiation From Within the Tumor

Internal radiotherapy using Y-90 microspheres that deliver targeted, high-dose tumor irradiation

Administers radioactive microspheres directly into tumor-feeding arteries

Provides localised radiation with minimal exposure to healthy liver tissue
Allows higher radiation doses than external beam radiotherapy

Causes gradual tumor necrosis while maintaining overall hepatic function

Effective even in lesions close to vital structures

Clinical Indications for TARE

Suitable for primary liver cancers and metastatic tumors confined predominantly to the liver

Hepatocellular carcinoma (early, intermediate, and advanced stages)

Liver metastases from colorectal, neuroendocrine, breast, and pancreatic cancers

Cholangiocarcinoma with liver-dominant disease

Patients unsuitable for surgery, ablation, or transarterial chemoembolization (TACE)

Bridge-to-transplant or downstaging therapy in eligible HCC patients

Control of bulky or multifocal liver tumors

Advantages & Clinical Benefits of TARE

Minimally invasive, well-tolerated therapy offering durable tumor control and survival benefits

Outpatient or short-stay procedure with rapid recovery

Lower systemic toxicity than chemotherapy

Can be used in patients with portal vein thrombosis

Leads to significant tumor shrinkage and disease stabilization

Improves quality of life and symptom control

Compatible with systemic therapies including immunotherapy and targeted agents

Allows repeat treatment if needed

Why Choose Us

Excellence in Advanced Nuclear Medicine, Precision Imaging, and Targeted Therapies

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Comprehensive services covering oncology, cardiology, and functional imaging needs

Decades of experience supported by global research, leadership, and innovation

Our Expert Doctors

About Doctor

Dr. Gayana Shankaramurthy

Nuclear Medicine and Theranostics Expert
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